Pharmacokinetics and relative bioavailability of an oral amoxicillin-apramycin combination in pigs.

A new compound granular premix of amoxicillin (20% w/w dry mass)/apramycin (5% w/w dry mass) was developed, and its pharmacokinetics and relative bioavailability were determined in pigs following oral administration following a cross-over study design. The pharmacokinetic parameters of amoxicillin (...

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Bibliographic Details
Main Authors: Chongshan Dai, Tingting Zhao, Xing Yang, Xilong Xiao, Tony Velkov, Shusheng Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5398684?pdf=render