A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells
Abstract Background In mammalian cells the endoplasmic reticulum (ER) comprises a highly complex reticular morphology that is spread throughout the cytoplasm. This organelle is of particular interest to biologists, as its dysfunction is associated with numerous diseases, which often manifest themsel...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04334-x |