Glucose sensing by carotid body glomus cells: potential implications in disease

Glucose sensing by carotid body glomus cells: potential implications in disease

The carotid body (CB) is a key chemoreceptor organ in which glomus cells sense changes in blood O2, CO2, and pH levels. CB glomus cells have also been found to detect hypoglycemia in both non-primate mammals and humans. O2 and low-glucose responses share a common final pathway involving membrane dep...

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Bibliographic Details
Main Authors: Lin eGao, Patricia eOrtega-Sáenz, María eGarcía-Fernández, Patricia eGonzález-Rodríguez, Candela eCaballero-Eraso, Jose eLopez-Barneo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Physiology
Subjects:
Carotid Body
Hypoglycemia
diabetes
Sleep Apnea
glucose sensing
intermittent hypoxia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00398/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00398/full

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