Tertiary Lymphoid Organs in Central Nervous System Autoimmunity

Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients. Autoreactive T cells are important drivers of the disease, however, the efficacy of B cell de...

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Bibliographic Details
Main Authors: Meike Mitsdoerffer, Anneli Peters
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Immunology
Subjects:
EAE
TLO
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00451/full