S1P Signalling Differentially Affects Migration of Peritoneal B Cell Populations In Vitro and Influences the Production of Intestinal IgA In Vivo

S1P Signalling Differentially Affects Migration of Peritoneal B Cell Populations In Vitro and Influences the Production of Intestinal IgA In Vivo

Introduction: Sphingosine-1-phosphate (S1P) regulates the migration of follicular B cells (B2 cells) and directs the positioning of Marginal zone B cells (MZ B cells) within the spleen. The function of S1P signalling in the third B cell lineage, B1 B cells, mainly present in the pleural and peritone...

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Bibliographic Details
Main Authors: Annabel Kleinwort, Felix Lührs, Claus-Dieter Heidecke, Martin Lipp, Tobias Schulze
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
peritoneal B cells
B1 B cells
sphingosine-1-phosphate (S1P)
mucosal immunity
lymphocyte trafficking
Online Access:http://www.mdpi.com/1422-0067/19/2/391

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http://www.mdpi.com/1422-0067/19/2/391

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