Endovascular equipoise shift in a phase III randomized clinical trial of sonothrombolysis for acute ischemic stroke

Background: Results of our recently published phase III randomized clinical trial of ultrasound-enhanced thrombolysis (sonothrombolysis) using an operator-independent, high frequency ultrasound device revealed heterogeneity of patient recruitment among centers. Methods: We performed a post hoc analy...

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Main Authors: Andrei V. Alexandrov, Georgios Tsivgoulis, Martin Köhrmann, Aristeidis H. Katsanos, Lauri Soinne, Andrew D. Barreto, Travis Rothlisberger, Vijay K. Sharma, Robert Mikulik, Keith W. Muir, Christopher R. Levi, Carlos A. Molina, Maher Saqqur, Dimitris Mavridis, Theodora Psaltopoulou, Milan R. Vosko, Jochen B. Fiebach, Pitchaiah Mandava, Thomas A. Kent, Anne W. Alexandrov, Peter D. Schellinger
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756286419860652