Type 1 conventional dendritic cells and interferons are required for spontaneous CD4+ and CD8+ T‐cell protective responses to breast cancer

Type 1 conventional dendritic cells and interferons are required for spontaneous CD4+ and CD8+ T‐cell protective responses to breast cancer

Abstract Objectives To better understand how immune responses may be harnessed against breast cancer, we investigated which immune cell types and signalling pathways are required for spontaneous control of a mouse model of mammary adenocarcinoma. Methods The NOP23 mammary adenocarcinoma cell line ex...

Full description

Bibliographic Details
Main Authors: Raphaël Mattiuz, Carine Brousse, Marc Ambrosini, Jean‐Charles Cancel, Gilles Bessou, Julie Mussard, Amélien Sanlaville, Christophe Caux, Nathalie Bendriss‐Vermare, Jenny Valladeau‐Guilemond, Marc Dalod, Karine Crozat
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
breast cancer
cancer immunosurveillance
CD4+ T cells
CD8+ T cells
cDC1
IFN‐γ
Online Access:https://doi.org/10.1002/cti2.1305

Internet

https://doi.org/10.1002/cti2.1305

Similar Items