Luseogliflozin, a SGLT2 Inhibitor, Does Not Affect Glucose Uptake Kinetics in Renal Proximal Tubules of Live Mice

Luseogliflozin, a SGLT2 Inhibitor, Does Not Affect Glucose Uptake Kinetics in Renal Proximal Tubules of Live Mice

Proximal tubules (PTs) take up most of the glucose in the glomerular filtrate and return it to peritubular capillary blood. Sodium-glucose cotransporter 2 (SGLT2) at the apical membrane takes up glucose into the cell. Glucose then flows across the cells and is transported to the interstitium via glu...

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Bibliographic Details
Main Authors: Anqi Zhang, Daisuke Nakano, Wararat Kittikulsuth, Yuka Yamashita, Akira Nishiyama
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
glucose handling
proximal tubules
intravital imaging
Online Access:https://www.mdpi.com/1422-0067/22/15/8169

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https://www.mdpi.com/1422-0067/22/15/8169

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