Self-assembled nanostructures of L-ascorbic acid alkyl esters support monomeric amphotericin B

Hypothesis: Amphotericin B (AmB) is a highly effective antimicrobial, with broad antimycotic and antiparasitic effect. However, AmB poor water-solubilisation and aggregation tendency limits its use for topical applications. We studied the capacity of nanostructures formed by alkyl esters of L-ascorb...

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Bibliographic Details
Main Authors: Natalia E. Nocelli, Yenisleidy de las Mercedes Zulueta Díaz, Marine Millot, María Luz Colazo, Raquel V. Vico, Maria Laura Fanani
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021001614