The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

Numerous carrier proteins intervene in protein transport from the cytoplasm to the nucleus in eukaryotic cells. One of those is importin α, with several human isoforms; among them, importin α3 (Impα3) features a particularly high flexibility. The protein NUPR1L is an intrinsically disordered protein...

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Bibliographic Details
Main Authors: José L. Neira, Bruno Rizzuti, Ana Jiménez-Alesanco, Olga Abián, Adrián Velázquez-Campoy, Juan L. Iovanna
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
circular dichroism
fluorescence
importin
intrinsically disordered protein (IDP)
isothermal titration calorimetry (ITC)
molecular docking
Online Access:https://www.mdpi.com/1422-0067/21/19/7428

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https://www.mdpi.com/1422-0067/21/19/7428

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