Variations in the Abortive HIV-1 RNA Hairpin Do Not Impede Viral Sensing and Innate Immune Responses

The highly conserved trans-acting response element (TAR) present in the RNA genome of human immunodeficiency virus 1 (HIV-1) is a stably folded hairpin structure involved in viral replication. However, TAR is also sensed by viral sensors, leading to antiviral immunity. While high variation in the TA...

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Bibliographic Details
Main Authors: Melissa Stunnenberg, John L. van Hamme, Atze T. Das, Ben Berkhout, Teunis B. H. Geijtenbeek
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/7/897