Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses.

Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses.

Infusion of human third-party mesenchymal stromal cells (MSCs) appears to be a promising therapy for acute graft-versus-host disease (aGvHD). To date, little is known about how MSCs interact with the body's innate immune system after clinical infusion. This study shows, that exposure of MSCs to...

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Bibliographic Details
Main Authors: Guido Moll, Regina Jitschin, Lena von Bahr, Ida Rasmusson-Duprez, Berit Sundberg, Lena Lönnies, Graciela Elgue, Kristina Nilsson-Ekdahl, Dimitrios Mougiakakos, John D Lambris, Olle Ringdén, Katarina Le Blanc, Bo Nilsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3128611?pdf=render

Internet

http://europepmc.org/articles/PMC3128611?pdf=render

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