Long-term Effects of Multiple Glucocorticoid Exposures in Neonatal Mice

Long-term Effects of Multiple Glucocorticoid Exposures in Neonatal Mice

Glucocorticoids (GCs) such as dexamethasone (DEX) or betamethasone are repeatedly administered for up to a month to prematurely born infants as a treatment for chronic lung dysfunction. Results of clinical trials have shown that the use of GCs in these infants induces long-term deficits in neuromoto...

Full description

Bibliographic Details
Main Authors: Susan E. Maloney, Kevin K. Noguchi, David F. Wozniak, Stephen C. Fowler, Nuri B. Farber
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Behavioral Sciences
Subjects:
glucocorticoid
dexamethasone
neuromotor deficits
motor co-ordination
complex activity wheel
cerebellum
internal granule layer
neuron loss
apoptotic cell death
Online Access:http://www.mdpi.com/2076-328X/1/1/4

Internet

http://www.mdpi.com/2076-328X/1/1/4

Similar Items