Synthesis, Characterization and Cytotoxicity of New Rotundic Acid Derivatives

Synthesis, Characterization and Cytotoxicity of New Rotundic Acid Derivatives

Rotundic acid (RA, 1), a natural compound, exhibits potent tumor cell growth inhibiting properties. To date there are no reports on derivatives of RA. Furthermore, the 28-COOH position of RA might make it unstable and induced serious gastrointestinal side effects when it was applied in vivo. Therefo...

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Bibliographic Details
Main Authors: Hui Wang, Xiao-Hong Yang, Quan-Cheng Zhao, Zhao-Jie Meng, Fa-Gui Yue, Jia-Ming Sun, Min-Lun Nan, Yu-Fang He
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Molecules
Subjects:
rotundic acid
amino acid derivative
synthesis
characterization
cytotoxicity
Online Access:http://www.mdpi.com/1420-3049/17/2/1278/

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http://www.mdpi.com/1420-3049/17/2/1278/

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