Cisd2 Protects the Liver from Oxidative Stress and Ameliorates Western Diet-Induced Nonalcoholic Fatty Liver Disease

Cisd2 Protects the Liver from Oxidative Stress and Ameliorates Western Diet-Induced Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic steatohepatitis (NASH), are the most common chronic liver diseases worldwide. However, drugs to treat NAFLD and NASH are an unmet clinical need. This study sought to provide evidence that Cisd2 is a molecular target for...

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Bibliographic Details
Main Authors: Yi-Long Huang, Zhao-Qing Shen, Chen-Hua Huang, Yuan-Chi Teng, Chao-Hsiung Lin, Ting-Fen Tsai
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Antioxidants
Subjects:
nonalcoholic fatty liver disease (NAFLD)
nonalcoholic steatohepatitis (NASH)
Cisd2
Western diet
transcriptomics
hepatocyte-specific knockout
Online Access:https://www.mdpi.com/2076-3921/10/4/559

Internet

https://www.mdpi.com/2076-3921/10/4/559

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