Anaplastic Lymphoma Kinase Rearrangement in Digestive Tract Cancer: Implication for Targeted Therapy in Chinese Population.

Anaplastic lymphoma kinase (ALK) rearrangements define a subgroup of lung cancer which is eligible to targeted kinase inhibition. The aim of this study is to observe the incidence rate of ALK fusion in a large cohort of Chinese digestive tract cancer patients.Tissue microarray (TMA) was constructed...

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Bibliographic Details
Main Authors: Jianming Ying, Chen Lin, Jian Wu, Lei Guo, Tian Qiu, Yun Ling, Ling Shan, Haitao Zhou, Dongbing Zhao, Jian Wang, Jianwei Liang, Jianjun Zhao, Yuchen Jiao, Ning Lu, Hong Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4683076?pdf=render