BRCA1 mRNA expression levels as an predictor of response to neoadjuvant chemotherapy in breast cancer

Background. Most modern studies are limited to the study of only germline mutations of the BRCA1 gene (most often 5382insC). And there are very few works that characterize the different somatic changes in the BRCA1 gene in the tumor, in particular the expression of this gene and its relation to the...

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Main Authors: M. M. Tsyganov, M. K. Ibragimova, I. V. Deryusheva, P. V. Kazantseva, E. Yu. Garbukov, E. M. Slonimskaya, N. V. Litviakov
Format: Article
Language:Russian
Published: ABV-press 2018-05-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
Online Access:https://umo.abvpress.ru/jour/article/view/136