Effects of simvastatin in abdominal sepsis in rats<A NAME="volta1"></A> Efeitos da sinvastatina na sepse abdominal em ratos

Effects of simvastatin in abdominal sepsis in rats<A NAME="volta1"></A> Efeitos da sinvastatina na sepse abdominal em ratos

PURPOSE: Statins are widely recognized as hypolipemic drugs, but some studies have observed anti-inflammatory and immunomodulatory effects, known as pleiotropic. The aims of this work was to study possible anti-inflammatory effects of simvastatin in abdominal sepsis. Serum pro-inflammatory cytokines...

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Bibliographic Details
Main Authors: José Luiz de Souza Neto, Irami Araújo Filho, Amália Cínthia Meneses do Rego, Víctor Almeida Dominici, Ítalo Medeiros Azevedo, Eryvaldo Sócrates Tabosa Egito, José Brandão-Neto, Aldo Cunha Medeiros
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2006-01-01
Series:Acta Cirurgica Brasileira
Subjects:
Estatina
Inflamação
Sepse abdominal
Rato Wistar
Citocinas
Leucócitos
Statin
Inflammation
Abdominal sepsis
Wistar rat
Cytokine
Leukocyte
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006001000003

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006001000003

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