The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice

NF-κB signaling pathways play an important role in the regulation of cellular immune and stress responses. Aberrant NF-κB activity has been implicated in almost all the steps of cancer development and many of the direct and indirect contributions of this transcription factor system for oncogenesis w...

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Bibliographic Details
Main Authors: Tabea Riedlinger, Jana Haas, Julia Busch, Bart van de Sluis, Michael Kracht, M. Lienhard Schmitz
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/6/1/36