iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice

Background. The epidemiologic association between pulmonary exposure to ambient particulate matter (PM) and acute lung damage is well known. However, the mechanism involved in the effects of repeated exposures of PM in the lung injury is poorly documented. This study tested the hypotheses that chron...

Full description

Bibliographic Details
Main Authors: Carla Máximo Prado, Renato Fraga Righetti, Fernanda Degobbi Tenorio Quirino dos Santos Lopes, Edna Aparecida Leick, Fernanda Magalhães Arantes-Costa, Francine Maria de Almeida, Paulo Hilário Nascimento Saldiva, Thais Mauad, Iolanda de Fátima Lopes Calvo Tibério, Mílton de Arruda Martins
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Pulmonary Medicine
Online Access:http://dx.doi.org/10.1155/2019/4781528