Key role of local regulation in chemosensing revealed by a new molecular interaction-based modeling method.

The signaling network underlying eukaryotic chemosensing is a complex combination of receptor-mediated transmembrane signals, lipid modifications, protein translocations, and differential activation/deactivation of membrane-bound and cytosolic components. As such, it provides particularly interestin...

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Bibliographic Details
Main Authors: Martin Meier-Schellersheim, Xuehua Xu, Bastian Angermann, Eric J Kunkel, Tian Jin, Ronald N Germain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020082