Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model

Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model

Abstract Background Disseminated tumor cells (DTCs) found in the bone marrow (BM) of patients with breast cancer portend a poor prognosis and are thought to be intermediaries in the metastatic process. To assess the clinical relevance of a mouse model for identifying possible prognostic and predicti...

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Bibliographic Details
Main Authors: Sreeraj G. Pillai, Shunqiang Li, Chidananda M. Siddappa, Matthew J Ellis, Mark A. Watson, Rebecca Aft
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Disseminated tumor cells
Patient-derived xenograft
Metastasis
Gene expression profile
Online Access:http://link.springer.com/article/10.1186/s13058-017-0927-1

Internet

http://link.springer.com/article/10.1186/s13058-017-0927-1

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