ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model

Imbalanced neuronal excitability homeostasis is commonly observed in patients with fragile X syndrome (FXS) and the animal model of FXS, the Fmr1 KO. While alterations of neuronal intrinsic excitability and synaptic activity at the steady state in FXS have been suggested to contribute to such a defi...

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Bibliographic Details
Main Authors: Dai-Chi Liu, Kwan Young Lee, Simon Lizarazo, Jessie K. Cook, Nien-Pei Tsai
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Neurobiology of Disease
Subjects:
FXS
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001996