High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method

High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method

<p>Abstract</p> <p>Background</p> <p>Aberrant DNA methylation leads to loss of heterozygosity (LOH) or loss of imprinting (LOI) as the first hit during human carcinogenesis. Recently we developed a new high-throughput, high-resolution DNA methylation analysis method, bi...

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Bibliographic Details
Main Authors: Hiura Hitoshi, Okae Hiroaki, Kobayash Hisato, Miyauchi Naoko, Sato Fumi, Sato Akiko, Suzuki Fumihiko, Nagase Satoru, Sugawara Junichi, Nakai Kunihiko, Yaegashi Nobuo, Arima Takahiro
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Medical Genomics
Subjects:
Genomic imprinting
Ovarian cancer
DNA methylation
Bisulphite PCR-Luminex(BPL)method
LOI (loss of imprinting)
Online Access:http://www.biomedcentral.com/1755-8794/5/8

Internet

http://www.biomedcentral.com/1755-8794/5/8

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