Severe Adverse Drug Reactions to Quetiapine in Two Patients Carrying <i>CYP2D6</i>*4 Variants: A Case Report

Severe Adverse Drug Reactions to Quetiapine in Two Patients Carrying <i>CYP2D6</i>*4 Variants: A Case Report

We report two cases of patients who developed severe adverse drug reactions including persistent movement disorders, nausea, and vertigo during treatment with quetiapine at maximum daily doses ranging between 300 and 400 mg. The extensive hepatic metabolism of quetiapine is mainly attributed to cyto...

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Bibliographic Details
Main Authors: Céline K. Stäuble, Markus L. Lampert, Thorsten Mikoteit, Martin Hatzinger, Kurt E. Hersberger, Henriette E. Meyer zu Schwabedissen
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
pharmacogenetics
pharmaceutical care
psychiatry
depression
neuroleptics
antipsychotics
Online Access:https://www.mdpi.com/1422-0067/22/12/6480

Internet

https://www.mdpi.com/1422-0067/22/12/6480

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