A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and β-Cell Function in Egyptian Type 2 Diabetic Patients

A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and β-Cell Function in Egyptian Type 2 Diabetic Patients

Aims: Serine protease inhibitor B1 (SerpinB1) is a neutrophil elastase inhibitor that has been proved to be associated with type 2 diabetes mellitus and pancreatic β-cell proliferation. In this study, we investigated 2 SERPINB1 SNPs, rs114597282 and rs15286, regarding their association with diabetes...

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Bibliographic Details
Main Authors: Dina H. Kassem, Aya Adel, Ghada H. Sayed, Mohamed M. Kamal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
serpinB1
type 2 diabetes mellitus
β-cell dysfunction
insulin resistance
hepatokines
gene polymorphism
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00450/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00450/full

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