Myoinositol CEST signal in animals with increased Iba-1 levels in response to an inflammatory challenge-Preliminary findings.

Neuroinflammation plays an important role in the pathogenesis of a range of brain disorders. Non-invasive imaging of neuroinflammation is critical to help improve our understanding of the underlying disease mechanisms, monitor therapies and guide drug development. Generally, MRI lacks specificity to...

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Bibliographic Details
Main Authors: Maria Yanez Lopez, Marie-Christine Pardon, Kerstin Baiker, Malcolm Prior, Ding Yuchun, Alessandra Agostini, Li Bai, Dorothee P Auer, Henryk M Faas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212002