Endogenous carbamylation of renal medullary proteins.

Protein carbamylation is a post-translational modification that can occur in the presence of urea. In solution, urea is in equilibrium with ammonium cyanate, and carbamylation occurs when cyanate ions react with the amino groups of lysines, arginines, protein N-termini, as well as sulfhydryl groups...

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Bibliographic Details
Main Authors: J'Neka S Claxton, Pablo C Sandoval, Gary Liu, Chung-Lin Chou, Jason D Hoffert, Mark A Knepper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873256?pdf=render