Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

Abstract Background Fibroblasts are the powerhouses responsible for the production and assembly of extracellular matrix (ECM). Their activity needs to be tightly controlled especially within the musculoskeletal system, where changes to ECM composition affect force transmission and mechanical loading...

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Bibliographic Details
Main Authors: Ching-Yan Chloé Yeung, Erwin M. Schoof, Michal Tamáš, Abigail L. Mackey, Michael Kjaer
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cell Communication and Signaling
Subjects:
Extracellular vesicle
Musculoskeletal tissue
Mass spectrometry
Extracellular matrix
Online Access:http://link.springer.com/article/10.1186/s12964-020-00669-9

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http://link.springer.com/article/10.1186/s12964-020-00669-9

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