Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks.

Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks.

Human gene regulatory networks (GRN) can be difficult to interpret due to a tangle of edges interconnecting thousands of genes. We constructed a general human GRN from extensive transcription factor and microRNA target data obtained from public databases. In a subnetwork of this GRN that is active d...

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Bibliographic Details
Main Authors: Vipin Narang, Muhamad Azfar Ramli, Amit Singhal, Pavanish Kumar, Gennaro de Libero, Michael Poidinger, Christopher Monterola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004504

Internet

https://doi.org/10.1371/journal.pcbi.1004504

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