VERO cells harbor a poly-ADP-ribose belt partnering their epithelial adhesion belt

Poly-ADP-ribose (PAR) is a polymer of up to 400 ADP-ribose units synthesized by poly-ADP-ribose-polymerases (PARPs) and degraded by poly-ADP-ribose-glycohydrolase (PARG). Nuclear PAR modulates chromatin compaction, affecting nuclear functions (gene expression, DNA repair). Diverse defined PARP cytop...

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Bibliographic Details
Main Authors: Laura Lafon-Hughes, Salomé C. Vilchez Larrea, Alejandra Kun, Silvia H. Fernández Villamil
Format: Article
Language:English
Published: PeerJ Inc. 2014-10-01
Series:PeerJ
Subjects:
PAR
Online Access:https://peerj.com/articles/617.pdf