Evaluation of GWAS candidate susceptibility loci for uterine leiomyoma in the multi-ethnic NIEHS uterine fibroid study

Evaluation of GWAS candidate susceptibility loci for uterine leiomyoma in the multi-ethnic NIEHS uterine fibroid study

We evaluated the association of 56 candidate SNPs identified in two published genome-wide association studies (GWAS) of uterine leiomyoma (UL), or fibroids, with the risk and tumor size in the multi-ethnic uterine fibroid study (NIEHS-UFS). The selected SNPs were genotyped in 916 premenopausal women...

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Bibliographic Details
Main Authors: Brahim eAissani, Kui eZhang, Howard eWiener
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Genetics
Subjects:
Extracellular Matrix
Reproductive Medicine
Meta-analysis
Genetic association
thrombospondin
African American
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00241/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00241/full

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