A bend, flip and trap mechanism for transposon integration

A bend, flip and trap mechanism for transposon integration

Cut-and-paste DNA transposons of the mariner/Tc1 family are useful tools for genome engineering and are inserted specifically at TA target sites. A crystal structure of the mariner transposase Mos1 (derived from Drosophila mauritiana), in complex with transposon ends covalently joined to target DNA,...

Full description

Bibliographic Details
Main Authors: Elizabeth R Morris, Heather Grey, Grant McKenzie, Anita C Jones, Julia M Richardson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
transposition
DNA integration
X-ray crystallography
base flipping
time-resolved fluorescence
base analogues
Online Access:https://elifesciences.org/articles/15537

Internet

https://elifesciences.org/articles/15537

Similar Items