MicroRNA-21: A Positive Regulator for Optimal Production of Type I and Type III Interferon by Plasmacytoid Dendritic Cells

MicroRNA-21: A Positive Regulator for Optimal Production of Type I and Type III Interferon by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are the major producers of type I and type III interferons (IFNs) that play essential roles in host antiviral immunity. MicroRNAs (miRs) are small, noncoding RNAs that can modulate many immune processes. Although molecular regulation of type I IFN production by pD...

Full description

Bibliographic Details
Main Authors: Fang Liu, Chunxi Liu, Xiaoyu Hu, Yingli Shang, Li Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
microRNA-21
innate immunity
interferons
toll-like receptors
plasmacytoid dendritic cell
phosphatase and tensin homolog
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00947/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00947/full

Similar Items