HiCancer: accurate and complete cancer genome phasing with Hi-C reads

Abstract Due to the high complexity of cancer genome, it is too difficult to generate complete cancer genome map which contains the sequence of every DNA molecule until now. Nevertheless, phasing each chromosome in cancer genome into two haplotypes according to germline mutations provides a suboptim...

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Bibliographic Details
Main Authors: Weihua Pan, Desheng Gong, Da Sun, Haohui Luo
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86104-6