Viral IL-10 Gene Transfer Prolongs Rat Islet Allograft Survival

Islet transplantation is a potential cure for diabetes. However, allotransplant rejection severely limits its clinical application. In this study, we sought to transfect rat islets with an adenoviral vector containing the viral IL-10 (vIL-10) gene and examine its efficacy in preventing graft rejecti...

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Bibliographic Details
Main Authors: Yang-Hee Kim, Dong-Gyun Lim, Yu-Mee Wee, Jin-Hee Kim, Chae-Ok Yun, Monica-Y. Choi, Youn-Hee Park, Song-Cheol Kim, Duck-Jong Han M.D.
Format: Article
Language:English
Published: SAGE Publishing 2008-06-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368908786092694