All-Optical Assay to Study Biological Neural Networks

All-Optical Assay to Study Biological Neural Networks

We introduce a novel all-optical assay for functional studies of biological neural networks in vitro. We created a novel optogenetic construct named OptoCaMP which is a combination of a channelrhodopsin variant (CheRiff) and a red genetically encoded calcium indicator (GECI) (jRCaMP1b). It enables s...

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Bibliographic Details
Main Authors: Wardiya Afshar Saber, Federico M. Gasparoli, Marjet G. Dirks, Frank J. Gunn-Moore, Maciej Antkowiak
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neuroscience
Subjects:
all-optical assay
optogenetics
calcium imaging
neural networks
connectivity
neurons
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00451/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00451/full

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