Differential importance of nucleus accumbens Ox1Rs and AMPARs for female and male mouse binge alcohol drinking

Abstract Alcohol use disorder exhausts substantial social and economic costs, with recent dramatic increases in female problem drinking. Thus, it is critically important to understand signaling differences underlying alcohol consumption across the sexes. Orexin-1 receptors (Ox1Rs) can strongly promo...

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Bibliographic Details
Main Authors: Claudina Kwok, Kelly Lei, Vincent Pedrozo, Lexy Anderson, Shahbaj Ghotra, Margaret Walsh, Laura Li, JiHwan Yu, Frederic Woodward Hopf
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79935-2