Vitamin D stimulates miR-26b-5p to inhibit placental COX-2 expression in preeclampsia

Abstract Vitamin D insufficiency or deficiency during pregnancy has been associated with an increased risk of preeclampsia. Increased placental cyclooxygenase-2 (COX-2) activity was proposed to contribute to the inflammatory response in preeclampsia. This study was to investigate if vitamin D can be...

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Bibliographic Details
Main Authors: Yang Cao, Xiaotong Jia, Yujia Huang, Jiao Wang, Chunmei Lu, Xiaolei Yuan, Jie Xu, Hui Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90605-9