Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic Diseases

Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic Diseases

Erythroblastic islands (EBIs), discovered more than 60 years ago, are specialized microenvironments for erythropoiesis. This island consists of a central macrophage with surrounding developing erythroid cells. EBI macrophages have received intense interest in the verifications of the supporting eryt...

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Bibliographic Details
Main Authors: Wei Li, Rongqun Guo, Yongping Song, Zhongxin Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
EBI macrophages
erythropoiesis
central macrophages
EPOR
erythroid hematopoietic disorders
β-thalassemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.613885/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.613885/full

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