Association between SLC19A1 gene polymorphism and high dose methotrexate toxicity in childhood acute lymphoblastic leukaemia and non Hodgkin malignant lymphoma: introducing a haplotype based approach

Association between SLC19A1 gene polymorphism and high dose methotrexate toxicity in childhood acute lymphoblastic leukaemia and non Hodgkin malignant lymphoma: introducing a haplotype based approach

We investigated the clinical relevance of SLC 19A1 genetic variability for high dose methotrexate (HD-MTX) related toxicities in children and adolescents with acute lymphoblastic leukaemia (ALL) and non Hodgkin malignant lymphoma (NHML).

Bibliographic Details
Main Authors: Kotnik Barbara Faganel, Jazbec Janez, Grabar Petra Bohanec, Rodriguez-Antona Cristina, Dolzan Vita
Format: Article
Language:English
Published: Sciendo 2017-09-01
Series:Radiology and Oncology
Subjects:
acute lymphoblastic leukaemia
genetic polymorphism
haplotype
methotrexate
Online Access:https://doi.org/10.1515/raon-2017-0040

Internet

https://doi.org/10.1515/raon-2017-0040

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