Trypanosoma cruzi Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease

Trypanosoma cruzi Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease

The clinical evolution of patients with chronic Chagas disease (CCD) is mainly associated with an excessive inflammation and a defective immunomodulatory profile caused by the interaction between T. cruzi and the host. Regulatory B (Breg) cells exert immune suppression mostly through IL-10 productio...

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Bibliographic Details
Main Authors: Magalí C. Girard, Micaela S. Ossowski, Arturo Muñoz-Calderón, Marisa Fernández, Yolanda Hernández-Vásquez, Raúl Chadi, Karina A. Gómez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
regulatory B cells
IL-10-producing B cells
chronic Chagas disease
human Trypanosoma cruzi infection
chronic Chagas cardiomyopathy
PD-L1
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.723549/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.723549/full

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