A systematic review and meta-analysis of preclinical trials testing anti-toxin therapies for B. anthracis infection: A need for more robust study designs and results.

B. anthracis anti-toxin agents are approved and included in the Strategic National Stockpile based primarily on animal infection trials. However, in the only anthrax outbreak an approved anti-toxin agent was administered in, survival did not differ comparing recipients and non-recipients, although r...

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Bibliographic Details
Main Authors: Wanying Xu, Lernik Ohanjanian, Junfeng Sun, Xizhong Cui, Dante Suffredini, Yan Li, Judith Welsh, Peter Q Eichacker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5552191?pdf=render