Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies

As the target organ for numerous pathogens, the lung epithelium exerts critical functions in health and disease. However, research in this area has been hampered by the quiescence of the alveolar epithelium under standard culture conditions. Here, we used human distal airway epithelial cells (DAECs)...

Full description

Bibliographic Details
Main Authors: Aki Imai-Matsushima, Laura Martin-Sancho, Alexander Karlas, Seiichiro Imai, Tamara Zoranovic, Andreas C. Hocke, Hans-Joachim Mollenkopf, Hilmar Berger, Thomas F. Meyer
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641830197X