Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer

Gastric cancer is the forth most frequent malignancy and the second most common cause of cancer death worldwide. DNA methylation is the most studied epigenetic alteration, occurring through a methyl radical addition to the cytosine base adjacent to guanine. Many tumor genes are inactivated by DNA me...

Full description

Bibliographic Details
Main Authors: E.M. Lima, M.F. Leal, R.R. Burbano, A.S. Khayat, P.P. Assumpção, M.J. Bello, J.A. Rey, M.A.C. Smith, C. Casartelli
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2008-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600017