Ginsenoside Rb1 Attenuates Oxygen-Glucose Deprivation-Induced Apoptosis in SH-SY5Y Cells via Protection of Mitochondria and Inhibition of AIF and Cytochrome c Release

Ginsenoside Rb1 Attenuates Oxygen-Glucose Deprivation-Induced Apoptosis in SH-SY5Y Cells via Protection of Mitochondria and Inhibition of AIF and Cytochrome c Release

To investigate the role of mitochondria in the protective effects of ginsenoside Rb1 on cellular apoptosis caused by oxygen-glucose deprivation, in this study, MTT assay, TUNEL staining, flow cytometry, immunocytochemistry and western blotting were used to examine the cellular viability, apoptosis,...

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Bibliographic Details
Main Authors: Pengfei Ge, Jizhou Zhang, Hongbo Zhang, Bin Lu, Boyu Wang, Ying Yu, Jianmin Liang
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
ginsenoside Rb1
oxygen-glucose deprivation
mitochondria
apoptosis inducing factor
cytochrome c
Online Access:http://www.mdpi.com/1420-3049/18/10/12777

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http://www.mdpi.com/1420-3049/18/10/12777

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