Antimicrobial screening and one-pot synthesis of 4-(substituted-anilinomethyl)-3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives

Antimicrobial screening and one-pot synthesis of 4-(substituted-anilinomethyl)-3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives

Aim: Synthesis of series of 4-(substituted-anilinomethyl-3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives (4a-4k) and their in vitro antifungal and antibacterial screening. Materials and Methods: A series of compounds (4a-4k) was synthesized through direct reductive amination of 3-(naphthalen-2-yl)-1...

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Bibliographic Details
Main Authors: Neelima Goel, Sushma Drabu, Obaid Afzal, Sandhya Bawa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Antimicrobial activity
naphthalene
pyrazole
reductive amination
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2014;volume=6;issue=4;spage=253;epage=259;aulast=Goel

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2014;volume=6;issue=4;spage=253;epage=259;aulast=Goel

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