Emergence of a Large-Plaque Variant in Mice Infected with Coxsackievirus B3
Coxsackieviruses are enteric viruses that frequently infect humans. To examine coxsackievirus pathogenesis, we orally inoculated mice with the coxsackievirus B3 (CVB3) Nancy strain. Using HeLa cell plaque assays with agar overlays, we noticed that some fecal viruses generated plaques >100 times a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-03-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/2/e00119-16 |