Carnitine Deficiency and Oxidative Stress Provoke Cardiotoxicity in an Ifosfamide-Induced Fanconi Syndrome Rat Model

In addition to hemorrhagic cystitis, Fanconi Syndrome is a serious clinical side effect during ifosfamide (IFO) therapy. Fanconi syndrome is a generalized dysfunction of the proximal tubule which is characterized by excessive urinary excretion of glucose, phosphate, bicarbonate, amino acids and othe...

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Bibliographic Details
Main Authors: Mohamed M. Sayed-Ahmed, Amal Q. Darweesh, Amal J. Fatani
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.4161/oxim.3.4.12859