Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke.

Inflammation is a pathophysiological hallmark of many diseases of the brain. Specific imaging of cells and molecules that contribute to cerebral inflammation is therefore highly desirable, both for research and in clinical application. The 18 kDa translocator protein (TSPO) has been established as a...

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Bibliographic Details
Main Authors: Denise Harhausen, Violetta Sudmann, Uldus Khojasteh, Jochen Müller, Marietta Zille, Keith Graham, Andrea Thiele, Thomas Dyrks, Ulrich Dirnagl, Andreas Wunder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936336/pdf/?tool=EBI